Big Decisions, Risks and Action

I recently received a few comments concerning my recent decision to embark on a new field of medicine which is fairly new but well commercialized. Some were supportive, but there were some who just don't get it.
Leaving my comfortable work to embark on a more commercialized industry may sound like a bit drastic. But before coming to such decisions, there were a lot of arguments and rationalizing done - and statistically, my chances of being more successful lies outside the window, not inside. I may be in the medical field, but yes we do learn about statistics, medical statistics to be more exact. We were taught how to calculate risks and define our inclusion and exclusion criteria, thus finally giving us odds ratio or p value to a certain significance.
It is pretty much the same with any decision making. First you need to define the decision properly, the objectives, the methods you wish to use to achieve the objectives, inclusion and exclusion criteria, then list down the benefits, and the risks, and calculate - whether the benefits are significant or not, whether the risks are significant or not.hen you come with a conclusion or a hypothesis, when enough evidence then it becomes a theory. Its not like I'm jumping the gun.
I have decided and like always, if I have decided, I normally would stick to my decision unless God forbades it. I'm just upset that a lot of people just don't respect other people's decisions.